Introduction | Creating a filematrix | Reading from and writing to a filematrix | Row and column names | Closing filematrices | Open or load an existing filematrix | By column access is faster then by rows | Appending columns | Deleting filematrix files | Version information

Working with large matrices | Accessing all matrix elements | Filling in matrix values | Calculating column sums | Calculating row sums | Removing filematrix after use | Version information

Motivation for creation of filematrix package | Differences between filematrix and bigmemory packages | Differences in tests | Example when filematrix is much more efficient than bigmemory

Overview | Permutation analysis on matched binary data sets | Enrichment testing for two sets of p-values \ | Enrichment testing with shiftR | Matching data sets by location