Package: MatrixEQTL 2.3

MatrixEQTL: Matrix eQTL: Ultra Fast eQTL Analysis via Large Matrix Operations

Matrix eQTL is designed for fast eQTL analysis on large datasets. Matrix eQTL can test for association between genotype and gene expression using linear regression with either additive or ANOVA genotype effects. The models can include covariates to account for factors as population stratification, gender, and clinical variables. It also supports models with heteroscedastic and/or correlated errors, false discovery rate estimation and separate treatment of local (cis) and distant (trans) eQTLs. For more details see Shabalin (2012) <doi:10.1093/bioinformatics/bts163>.

Authors:Andrey A Shabalin [aut, cre]

MatrixEQTL_2.3.tar.gz
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MatrixEQTL.pdf |MatrixEQTL.html
MatrixEQTL/json (API)

# Install 'MatrixEQTL' in R:
install.packages('MatrixEQTL', repos = c('https://andreyshabalin.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/andreyshabalin/matrixeqtl/issues

Datasets:
  • Covariates - Artificial data for Matrix eQTL sample code: Covariates.
  • GE - Artificial data for Matrix eQTL sample code: Gene expression.
  • SNP - Artificial data for Matrix eQTL sample code: Genotype.
  • geneloc - Artificial data for Matrix eQTL sample code: Gene location file.
  • snpsloc - Artificial data for Matrix eQTL sample code: SNP location file.

On CRAN:

8.10 score 69 stars 2 packages 612 scripts 637 downloads 81 mentions 19 exports 0 dependencies

Last updated 1 years agofrom:f88f97e07a. Checks:1 OK, 7 ERROR. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKFeb 19 2025
R-4.5-winERRORFeb 19 2025
R-4.5-macERRORFeb 19 2025
R-4.5-linuxERRORFeb 19 2025
R-4.4-winERRORFeb 19 2025
R-4.4-macERRORFeb 19 2025
R-4.3-winERRORFeb 19 2025
R-4.3-macERRORFeb 19 2025

Exports:as.matrixcolMeanscolnamescolnames<-colSumsMatrix_eQTL_engineMatrix_eQTL_mainmodelANOVAmodelLINEARmodelLINEAR_CROSSncolNCOLnrowNROWrowMeansrownamesrownames<-rowSumsSlicedData

Dependencies:

Readme and manuals

Help Manual

Help pageTopics
Matrix eQTL: Ultra Fast eQTL Analysis via Large Matrix OperationsMatrixEQTL-package MatrixEQTL
Artificial data for Matrix eQTL sample code: Covariates.Covariates
Artificial data for Matrix eQTL sample code: Gene expression.GE
Artificial data for Matrix eQTL sample code: Gene location file.geneloc
Main function for fast eQTL analysis in MatrixEQTL packageMatrix_eQTL_engine Matrix_eQTL_main
Sample code for cis/trans-eQTL analysis with Matrix eQTLMatrixEQTL_cis_code
Constant for 'Matrix_eQTL_engine'.modelANOVA
Constant for 'Matrix_eQTL_engine'.modelLINEAR
Constant for 'Matrix_eQTL_engine'.modelLINEAR_CROSS
Plot histogram or QQ-plot of all p-valuesplot.MatrixEQTL
Class 'SlicedData' for storing large matricesas.matrix,SlicedData-method colMeans,SlicedData-method colnames,SlicedData-method colnames<-,SlicedData-method colSums,SlicedData-method dim,SlicedData-method length,SlicedData-method NCOL,SlicedData-method ncol,SlicedData-method NROW,SlicedData-method nrow,SlicedData-method rowMeans,SlicedData-method rownames,SlicedData-method rownames<-,SlicedData-method rowSums,SlicedData-method show,SlicedData-method SlicedData SlicedData-class summary.SlicedData [[,SlicedData-method [[<-,SlicedData-method
Artificial data for Matrix eQTL sample code: Genotype.SNP
Artificial data for Matrix eQTL sample code: SNP location file.snpsloc